CD8A and neoplasm: The results showed that RAC2 expression was significantly positively correlated with the levels of tumor-filtrating immune cells, including CD8+ T cells (p < 0.0001), follicular helper T cells (p < 0.0001), and regulatory T cells (Tregs) (p < 0.0001), and negatively correlated with naive B cells and resting mast cells (p < 0.0001) (Figure 6A).