However, our bioinformatics analysis of the TCGA database also showed that NEDD4L is highly expressed in cervical cancer, cholangiocarcinoma, head and neck squamous cell carcinoma, and renal chromophobe, and there is no difference in NEDD4L expression in adrenocortical carcinoma, pancreatic adenocarcinoma, pheochromocytoma, thyroid cancer, and thymoma compared to normal tissue. This evidence concerns the gene NEDD4L and thyroid cancer.