TRIB2 and infection: Evidence supporting the immune-mediated mechanisms includes the detection of anti-Tribbles homolog 2 (TRIB2) [24] and anti-streptococcal antibodies [23] in patients with NT1, the seasonal patterns observed in the onset of NT1 [19], and the heightened incidence of NT1 following infections and vaccinations related to the H1N1 influenza virus [63].