OTX2 and colorectal carcinoma: Remarkably, the expression levels of OCT3/4 (p = 0.009), SOX2 (p = 0.0428), NANOG (p = 0.031), OTX2 (p = 0.0423), VEGF (p = 0.0139), SOX17 (p = 0.0282) and PDX-1 (p = 0.0247) were significantly higher in MZ-CRC-1 cells compared to TT cells (Figure 1A,B).