PRL and COVID-19: Notably, in a cohort of climacteric women with moderate COVID-19, prolactin levels were significantly elevated during the acute phase of infection, alongside reductions in estradiol, testosterone, and other key hormones; however, at 12 months post-infection, prolactin levels had significantly decreased in 73.3% of these patients compared to their acute phase levels (p = 0.041) [42].