ANGPT2 and cholesteatoma: miR106b-5p binds to the 3′UTR of angiopoietin 2 to induce the migration and tube formation of human umbilical vein endothelial cells; and human cholesteatoma peri-matrix fibroblasts-derived exosomes transport miR106b-5p to endothelial cells and promote angiogenesis via upregulating the expression of angiopoietin 2 [98].