Platelet-derived miR223 inhibits VSMC differentiation and restores Kawasaki-disease-induced vascular injury through the inhibition of PDGFRβ; miR143 and miR145 target Krüppel-like factor (KLF) 4 and 5, respectively, to suppress VSMC dedifferentiation (Figure 2a) [29,30]. Here, PDGFRB is linked to Kawasaki disease.