Based on such findings, in this study, APN, Me-APN, Cbz-APN and Bzn-APN were used at 25 μM alone and in combination with 10 μM proTAME and tested in MDA-MB-231 triple-negative breast cancer and HeLa cervical cancer cells (Figure 6A,B). The gene discussed is ANPEP; the disease is triple-negative breast carcinoma.