Additionally, we identified a group of hub genes, namely PRDX1, ACTB (actin beta), APBB1IP (amyloid beta precursor protein binding family B member 1 interacting protein), CYFIP1 (cytoplasmic FMR1 interacting protein 1), and PGD (hosphogluconate dehydrogenase), which exhibited high expression in stroke and significant downregulation of gene expression under IPostC. Here, PRDX1 is linked to stroke disorder.