Additionally, we identified a group of hub genes, namely PRDX1, ACTB (actin beta), APBB1IP (amyloid beta precursor protein binding family B member 1 interacting protein), CYFIP1 (cytoplasmic FMR1 interacting protein 1), and PGD (hosphogluconate dehydrogenase), which exhibited high expression in stroke and significant downregulation of gene expression under IPostC. This evidence concerns the gene ACTB and stroke disorder.