S100A8 and psoriasis: In a report of Chen, et al., in a mouse model of IMQ-induced psoriasis-like skin inflammation MSCs significantly reduced the expression level of proinflammatory cytokines (IL-17, IL-23, IL-6, and IL-1β) and keratinocyte differentiation markers (S100A7, S100A8, and S100A9), and they remarkably increased the expression level of anti-inflammatory cytokine IL-10 [136].