GSDMB and neoplasm: GSDMB is expressed in humans but not in mice, with five reported subtypes: GSDMB3 and GSDMB4 can induce pyroptosis in tumor cells, while GSDMB1, GSDMB2, and GSDMB5 inhibit the cytotoxic effects of GSDMB3 and GSDMB4 [41].