TP53 and cancer: In this study, the cytotoxicity and antiproliferative effects of GA, which has a high anticancer, anti-inflammatory, and antioxidant potential [14,15,16] on the human HeLa cell line, were compared and combined with a powerful chemotherapeutic agent such as DOX, and its ability to be an alternative treatment was investigated and to potentiate the anti-cancer effects of GA/DOX combination was investigated by performing MTT method, apoptotic staining, and RT-PCR for proapoptotic P53 and Bax genes.