In the third trimester, the risk of gestational hypertension was impacted by the levels of sEng and the sFlt-1/PlGF ratio: OR 1.37 CI95 (1.05;1.91), p = 0.028, and OR 7.49 CI95 (1.57;71.74), p = 0.039, respectively. This evidence concerns the gene PGF and preeclampsia.