In our prior research, we investigated the impact of four Hero genes—C9orf16 (Hero9) [45], SERBP1 (Hero45) [46], SERF2 (Hero7) [47], and C19orf53 (Hero11) [48]—on ischemic stroke risk, finding a notable association between these genes and the disease. The gene discussed is C19orf53; the disease is ischemic stroke.