IL4 and allergic disease: Curran and Bertics in their publication regarding gliomas made some interesting observations: Firstly, immunity of atopic conditions, high total IgE, IL-4 activation, and, in consequence, eosinophil action may promote anticancer processes; thus, secondly, there were some data published that are in line with that hypothesis; allergy, asthma, and eczema diagnoses were associated with lower HR for glioma development (OR = 0.34–0.96, dependent on the study) [24].