CLIC4 expression levels were positively correlated with specific markers of macrophages (CD80, CD86, MRC1), neutrophils (FCGR3A, FCGR3B), eosinophils (SIGLEC8, IL3RA), T cells (CD3D, CD4), CD8+ T cells (CD8A, CD8D), NK cells (NCAM1), and B cells (CD19) in glioma (Figure 8C). The gene discussed is SIGLEC8; the disease is central nervous system cancer.