Fabry disease (FD, OMIM #301500) is an X-linked genetic metabolic disease caused by pathogenic variants in the GLA gene (HUGO Gene Nomenclature Committee ID: 4296; Gene Entrez: 2717; NCBI reference sequence: NM_000169.3) and thus a deficiency in activity of the lysosomal alpha-galactosidase A (α-Gal A, Enzyme Commission number: EC 3.2.1.22; UniProt ID: P06280). Here, GLA is linked to Fabry disease.