Some are treated with drugs, such as desferoxamine (DFO), Thymoquinone (TQ), Tongluo Shenggu Capsule (TLSGC), and astragaloside IV (AS-IV), which have also been shown to promote osteogenesis and angiogenesis through the VEGF pathway, thereby preventing or treating ANFH [70,71,72,73]. Here, VEGFA is linked to familial avascular necrosis of femoral head.