NFIB and glioblastoma: For example, cyclic adenosine monophosphate (cAMP) activators can induce the neuronal differentiation of GSCs [3], the upregulation of the expression of the transcription factors nuclear factor 1 A (NFIA) and nuclear factor 1 B (NFIB) can induce the differentiation of GBM cells into astrocytes [4], and the downregulation of zinc finger protein 117 (ZNF117) expression can induce the differentiation of GSCs into oligodendrocytes [5].