The 10 enrichment pathways identified through the KEGG pathway analysis were involved in signal transduction (e.g., FoxO signaling pathway, HIF-1 signaling pathway, AMPK signaling pathway), aging (e.g., longevity-regulating pathway), and human diseases (e.g., prostate cancer, melanoma, glioma, pancreatic cancer, etc.)(Figure 6 and Table S2). The gene discussed is HIF1A; the disease is familial pancreatic carcinoma.