NEFL and spinal muscular atrophy, type III: Meanwhile, in the study of Faravelli and colleagues, the concentrations of pNfH and NfL in the CSF of SMA type III patients aged 9–74 years significantly decreased 6 months after nusinersen administration compared to baseline levels, which were similar to those observed in controls, although the decline in pNfH and NfL levels was minor and did not correlate with HFMSE values [220].