These measurements of DNA methylation (M-values) for all three CpG loci located within the ZNF671 promoter showed significantly increased DNA methylation in the primary tumor DNA compared with matching non-tumor tissue DNA from the same patient (cg08048222: −1.17 ± 2.43 (tumor) versus −4.49 ± 0.66 (non-tumor) p < 0.001, cg19246110: −0.80 ± 2.12 (tumor) versus −3.65 ± 0.92 (non-tumor) p < 0.001), and cg21305471: −1.92 ± 2.27 (tumor) versus −4.91 ± 0.55 (non-tumor) p < 0.001) (Figure 1A–C). The gene discussed is ZNF671; the disease is neoplasm.