Authors found that the S100A14 protein played a role in cell invasion by influencing the expression and functionality of matrix metalloproteinase (MMP)-2 [50]; as well as enhancing the motility of breast cancer cells by increasing the S100A14 gene level [51]; furthermore, it enhanced the invasive activity of breast cancer cells through its interaction with cytoskeletal dynamics, suggesting its potential as a prognostic biomarker and a possible target for therapeutic interventions [52]. This evidence concerns the gene S100A14 and breast cancer.