AIFM2 and lung adenocarcinoma: Among lung adenocarcinoma cells, A549 and ABC-1 cells are cells with relatively lower GPX4 expression than other lung adenocarcinoma cells such as VMRC-LCD and RERF-LC-MS cells (Supplementary Figure S2), which may be relatively well suited to deplete GPX4 and FSP1 and induce ferroptosis.