CSF3 and acute myeloid leukemia: R/R AML is commonly treated with intensive salvage chemotherapy comprising a high-dose cytarabine backbone in combination with an anthracycline, including fludarabine, cytarabine, granulocyte colony stimulating factor with idarubicin (FLAG-IDA), mitoxantrone, etoposide, cytarabine (MEC), cladribine, cytarabine, granulocyte colony stimulating factor (CLAG) or high-dose cytarabine and mitoxantrone (HAM) in combination with GO [2,4,5,9].