For example, t(11;19)(q23;p13.1) ELL::KMT2A was the most common rearrangement in the mature monocytic phenotype, followed by t(9;11)(p22;q23) MLLT3::KMT2A, whereas t(9;11) (p22;q23) MLLT3::KMT2A was the most frequent rearrangement in the immature monocytic, APL-like, and myelomonocytic phenotypes. This evidence concerns the gene MLLT3 and acute promyelocytic leukemia.