In CD3-CD56+ cells, mean TLR-2 expression was 13.37 ± 10.41 in GC and 1.24 ± 0.84 in HV, TLR-3: 7.65 ± 5.50 in GC and 1.26 ± 0.87 in HV, TLR-4: 12.31 ± 8.99 in GC and 1.27 ± 0.90 in HV, and TLR-9: 12.42 ± 9.53 in GC and 1.26 ± 0.87 in HV, with p = 0.000 for all comparisons. Here, TLR9 is linked to gastric cancer.