The percentage of TLR expression on CD3-CD56+bright and CD3+CD56+ cells also showed high AUC values, especially for TLR2+ and TLR3+, where the AUC was 1.0 in most comparisons (p < 0.0001), highlighting their high specificity and sensitivity in differentiating GC stages. The gene discussed is TLR3; the disease is gastric cancer.