KLK6 and adenoma: Histopathology analysis of cellular dysplasia in the adenomas of CPC;Apcfl/fl;Klk6+/+, CPC;Apcfl/fl;Klk6+/fl, and CPC;Apcfl/fl;Klk6fl/fl mice showed that the number of low-grade adenomas in the small intestine was similar in mice with different zygosity of the Klk6 gene, ranging from 1.5 to 2 adenomas/mouse (Table 2 and Table 3, p = 0.65).