Overall, the total number of adenomas per mouse was significantly higher in the CPC;Apcfl/fl;Klk6+/+ mice (15.5 ± 4.22) and CPC;Apcfl/fl;Klk6+/fl mice (15.00 ± 5.47) than in the CPC;Apcfl/fl;Klk6fl/fl mice (8.83 ± 4.78) (p = 0.005). The gene discussed is KLK6; the disease is adenoma.