KLK6 and adenoma: Specifically, the higher percentage of adenomas with sizes 2.0–3.0 mm and above 3.0 mm was seen in CPC;Apcfl/fl;Klk6+/+ mice compared to the CPC;Apcfl/fl;Klk6+/fl and CPC;Apcfl/fl;Klk6fl/fl mice (p = 0.0018 and p = 0.0001, respectively).