KLK6 and adenoma: At the same time, the two-fold increase in the percentage of adenomas less than 2 mm was observed in the mice of CPC;Apcfl/fl;Klk6+/fl and CPC;Apcfl/fl;Klk6fl/fl genotypes (31.25% and 35.96%, respectively) compared to CPC;Apcfl/fl;Klk6+/+ mice (18.68%).