Moreover, it was recently shown that mutations in GNAS were more common in colloid-type IPMN with invasive carcinoma features than tubular-type IPMN with such characteristics (89% vs. 32%, respectively; p = 0.0003), whereas KRAS mutations were typical of tubular-type versus colloid-type IPMN (89% vs. 52%, respectively; p = 0.01). Here, GNAS is linked to pancreatic intraductal papillary-mucinous neoplasm.