Additionally, an in vivo study using humanized AR transgenic adenocarcinoma of mouse prostate (TRAMP) mice, created by recombining a human AR (CAG)(12, 21, or 48) DNA fragment with the mouse Ar gene, demonstrated that longer microsatellites provided an effect that was more protective against PCa development (PCa incidence: 85%, 52%, and 28%, respectively) [30]. The gene discussed is AR; the disease is posterior cortical atrophy.