However, the fact that bisecting GlcNAc structures are overexpressed in PC does not necessarily mean the same trend pertains in other cancers, although an increased expression of bisecting GlcNAc in prostatic fluids (rich in PSA and PAP) was shown during cancer progression in 2013 [154], while a decrease was observed in hormonally treated tumors [155]. Here, KLK3 is linked to cancer.