PHA-L has attracted attention due to the fact that specific N-acetylglucosaminyltransferases (GnT-III, GnT-IVs, GnT-IX (Vb) or, especially, GnT-V encoded by the MGAT5 gene, as probably the most characterized cancer-associated glycosyltransferases) play an important role in cancer progression, so this lectin can help identify a carcinogenesis early on [151,152]. The gene discussed is MGAT5; the disease is cancer.