ANXA2 and cancer: ANXA2 increases the invasive and metastatic potential of CRC cells by EMT via the LINC00460/miR-433-3p/ANXA2 Axis [81], by increasing the expression and polymerization of F-actin and β-tubulin and suppressing cell contact inhibition [85], as well as by affecting specific motility-associated micro-structures of cancer cells [87].