NF1 and neoplasm: This demonstrates the importance and suitability of using PET imaging in the routine follow-up of patients with NF1 in whom a higher risk of developing MPNSTs might be expected, such as those with the whole-gene deletions of NF1 [28], a high tumor burden including a large number of/or expansive plexiform neurofibroma, and large or rapidly growing tumor lesions [29].