Many hallmarks of cancer are impacted such as proliferation, cell survival, angiogenesis, vasculogenesis, metabolism and apoptosis by repression of miR-15a/16-1, miR-28, miR-29, and miR-34α, upregulated of miR-17-92, miR-106a/b, miR-20a, miR-93, miR-17, and miR-23a/b or cooperation of c-MYC with miR-548 and miR-155 for example. This evidence concerns the gene MYC and cancer.