Building on these observations, we found that, while olaparib and the downregulation of CX3CR1 were more effective in radiosensitizing the irradiated BRCA wild-type tumor cell line Caov-3 [30], which is HR-proficient [31], all three interventions, including CX3CR1 downregulation, olaparib, and X-ray radiation, were significantly more effective when used together (Figure 1). This evidence concerns the gene CX3CR1 and neoplasm.