Mutations in Dync1h1, which encodes the heavy chain of cytoplasmic dynein, have further been reported to affect cortical development, leading to conditions such as microcephaly and abnormalities in brain structures, including nodular heterotopia, hypoplasia of the corpus callosum, and dysmorphism of the basal ganglia [33,34,35]. The gene discussed is SLC3A2; the disease is microcephaly.