GALC and lysosomal storage disease: GLD, commonly referred to as Krabbe disease, is an autosomal lysosomal storage disease caused by deficiency of lysosomal enzyme galactocerebrosidase (GALC), which catabolizes the degradation of galactosyl-ceramide in the initial step of myelination synthesis and the degradation of toxic galactosyl-sphingosine (psychosine) [33,34].