Yildirim et al. [9] demonstrated that AMD reduced antioxidant defenses and increased oxidative stress in vivo by measuring the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), as well as oxidized protein products, malondialdehyde (MDA), glutathione (GSH), and vitamin C in 25 patients with AMD. Here, SOD1 is linked to age-related macular degeneration.