SLC5A2 and hydrops fetalis: In a meta-analysis that combined both trials, the SGLT2 inhibitors demonstrated a consistent reduction in the composite of CV-related death or first HF hospitalization, with HR 0.88, 95% CI 0.77–1.00 for CV-related death and HR 0.74, 95% CI 0.67–0.83 for HF hospitalization [342].