TIA1 and melanoma: Likewise, TIA1 is modulated by miR-27b, among others, which is widely associated with melanoma development, as described in 2021 by Yi Tian and collaborators, where they determined expression levels in melanoma cells and normal tissues by immunoelectrotransfer, correlating a negative regulation with MYC, a gene related to the Wnt-β catenin pathway—a pathway of importance in melanogenesis described previously—as a target in this case [126].