CRP and inflammation: The analysis revealed three principal factors with the following contributions: (1) Micro/macroscopic changes related to chronic inflammation and high-frequency CRP, with a correlation coefficient (CC) of 0.837; (2) high levels of CRP and microscopic acute inflammation, with a CC of 0.792; and (3) clinical activity scores ASDAS-CRP/BASDAI, with a CC of 0.914.