Hongo et al. reported that patients using a PPI presenting with FGP did not have high gastrin levels (approximately 200 pg/mL); however, high gastrin levels (>400 pg/mL) significantly increased the risk of hyperplastic polyps (Hazard ratio = 4.923; 95% CI, 1.486–16.31) [29]. The gene discussed is GAST; the disease is hyperplastic polyp.