NPPB and heart failure: The patients with NT-proBNP levels > 10,000 pg/mL were significantly older compared to groups A and B. These findings correlate with the studies published by Kokkindis et al. and Chandrashekhar et al., which found that older patients with heart failure have an increased risk of sarcopenia induced by heart failure, and a subsequent decrease in body weight at admission [22,23].