The area under the ROC curve for the level of NT-proBNP and the diagnosis of HF without renal impairment was 0.426 (p = 0.026, 95% CI [0.361–0.49]), and for NT-proBNP level and renal impairment was 0.574 (p = 0.026, 95% CI [0.511–0.639]), reaching the statistical significance threshold in both situations. This evidence concerns the gene NPPB and hydrops fetalis.