When adjusted for age, the factors significantly or nominally associated with incident AS were systolic blood pressure, body mass index, waist, waist/hip ratio, body fat mass and fat-free mass percentages, urine albumin, urine albumin excretion rate, hs-CRP, fasting plasma insulin and proinsulin, OGTT 30 min plasma insulin and proinsulin, OGTT 120 min plasma insulin and proinsulin, serum C-peptide and Matsuda index. Here, INS is linked to aortic stenosis.