CD14 and ventilator-associated pneumonia: Importantly, the crucial antigen-presenting molecule HLA-DR was significantly but only transiently upregulated in non-classical monocytes (ncMono, CD3 ̄CD56 ̄CD19 ̄CD20 ̄HLA-DR+CD14 ̄CD16+) (Supplementary Fig. 1) in VAP at 24 h following AIT launch (Fig. 4g).