FTO and neurodegenerative disease: For example, mupirocin, entacapone, compounds “18,077” and “18,079”, several quinolone derivatives, and a series of 1,2,3-triazole analogs have been identified as potential FTO inhibitors.699–703 Notably, quinolone derivatives and their antitumor properties have shown the potential to improve symptoms in neurodegenerative diseases by inhibiting FTO activity.702 These findings broaden the potential clinical applications of FTO inhibitors.