ADAR and cancer: For instance, some cancer cells become dependent on adenosine‐to‐inosine (A‐to‐I) editing of IR‐Alus by the deaminase ADAR1, compromising the double‐stranded structure of Alu elements [3], while other cancer cells become dependent on IR‐Alu dsRNA decay by the exonuclease XRN1 [6, 7].