Considering that the same morphological and proliferation-related features are also linked to GBM invasiveness (Bhaduri et al, 2020; Venkataramani et al, 2022b), we generated neurospheres from FACS-sorted GFP+ cells overexpressing ADD3 or control plasmid and examined their infiltration into the surrounding Matrigel. The gene discussed is ADD3; the disease is glioblastoma.