MTOR and type 2 diabetes mellitus: Furthermore, lipokines, such as 12‐HEPE, from BAT enhance GLUT4‐mediated glucose uptake in skeletal muscle and BAT via the PI3K–mTOR–Akt–Glut signalling pathway, improving glucose tolerance and presenting a potential therapeutic target for T2D (Leiria et al., 2019; Shaikh et al., 2022).