TAB3 and hepatocellular carcinoma: For example, miR-23b is significantly downregulated in primary HCC [61], miR-24 promotes cell growth and is a prognostic indicator for multiple cancers [62], and miR-27b-3p inhibits HCC by targeting TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 3 (TAB3, [63]).