In particular, when comparing donors with a detectable CD8+ T cell response, the proportion of virus-specific CD8+ T cells with measurable degranulation (CD107a: 7/13 [53.85%] in MM patients vs. 38/43 [88.37%] in HCs, p = 0.0060) and cytokine production (IFNγ: 9/13 [69.23%] in MM patients vs. 39/43 [90.69%] in HCs, p = 0.0526; TNF: 7/13 [53.85%] in MM patients vs. 37/43 [85.04%] in HCs, p = 0.0132) was lower in the MM patients in comparison to HCs (Figure 2F). This evidence concerns the gene TNF and Miyoshi myopathy.