In previous studies on the functional characterization of genes related to the BPH, it was found that NlML1 (myeloid differentiation factor 2 (MD-2)-related lipid-recognition 1) [40] and NlSPARC (Secreted protein, Acidic and Rich in Cysteine) [41] were highly expressed in the fat body. Here, SPARC is linked to benign prostatic hyperplasia.